QFM-4000 Quench Flow Module

Microvolume quench flow

Quench flow is the method for tracking kinetics of non-optically active solutions.

Typically two reagents are mixed, the mixture flows through a delay line at a defined flow rate to be aged and finally the reaction is stopped with a quencher.

QFM-4000 has been designed for working with microvolumes solutions as low as 10 µL and minimum manipulation. For example the instrument uses one single delay line of 3 µL and ageing times covered with this line ranges 3-4 ms to few seconds without rearrangement!

Applications

- Molecule radioactive labeling

- Protein folding : H/De exchanges

- Second messenger studies

- Conformational changes

- And much more?